Backbench MPs raised the Copenhagen summit, flood management and the cost of the Olympics at prime minister's questions today.
Doug Naysmith (Lab, Bristol North West) said that following recent events in Colchester and Basildon Hospital, patient safety must be a priority for the NHS.
Gordon Brown said that there was "no excuse" for anything but the best care in the health service. He said patient safety "is and has to be" the NHS' number one priority.
Brown and Conservative leader David Cameron clashed over the economy, while Liberal Democrat leader Nick Clegg told Brown not to rely too heavily on Afghan president Hamid Karzai.
Lynda Waltho (Lab, Stourbridge) urged the government to do more to tackle domestic violence, which she said was the most "evil of crimes, and cowardly of crimes".
The prime minister said "real progress" had been made, but a "great deal" was left to be done.
Celia Barlow (Lab, Hove) praised Rayner Opticians, located in her constituency, and their work to address sight loss.
The prime minister, who himself suffers from sight problems, said those who contributed to the success of ophthalmic medicine had given Britain inventions that were "truly wonderful".
Ben Wallace (Con, Lancaster and Wyre) said recently released figures showed 140 inmates had died of cancer in British prisons since 2001.
Reffering to the release of the Lockerbie bomber Abdelbaset Ali Mohmed Al Megrahi he said:
"Is it one rule for British inmates and another for Libyan mass murderers?"
Brown said the decision to release Al Megrahi was for Scotland not the UK government in Westminster.
Roger Berry (Lab, Kingswood) called on Brown to do everything possible to secure a climate change deal at the upcoming Copenhagen summit.
The prime minister said he was looking forward to a successful summit.
Anne McIntosh (Con, Vale of York) sought assurances that local authorities would not be out of pocket when recovering from floods.
Brown said investment in flood management was "higher than ever".
Chris Ruane (Lab, Vale of Clwyd) attacked the Conservative and Liberal Democrat policies on the economy.
He said that the "dynamic duo" of Cameron and Clegg wanted to adopt "immediate and savage" cuts that would prevent Britain from recovering from the recession.
It would be a "right old Eton mess" he added.
Brown said the action the government had taken to help small business was supported by every other country in the world.
Malcolm Bruce (Lib Dem, Gordon) said securing a commitment to the £100bn climate change fund in 2020 would be "essential" to securing a deal from developing countries.
But the chairman of the international development committee said the government also had to ensure that Britain was able to deal with the effects of climate change at home.
Brown said that there was "no doubt" about the scientific evidence for climate change.
He indicated that there would be measures in the pre-budget report on investing in a low carbon economy and tackling climate change.
Tom Harris (Lab, Glasgow South) asked whether the prime minister thought every candidate who stands for election to the Commons should pay taxes in UK.
"Yes," Brown responded.
Gregory Barker (Con, Bexhill and Battle) criticised the government for allowing the "key economic portfolio" in the EU to go to France.
"Why did the prime minister fail to win it for Britain?" he asked.
Brown said the policies that were being adopted by the EU were a result of British proposals and British influence.
Dai Havard (Lab, Merthyr Tydfil and Rhymney) asked about the civil service compensation scheme.
Brown said he could not defend the current system that allows top civil servants to receive six times the ordinary salary.
Elfyn Llwyd (PC, Meirionnydd Nant Conwy) said there had been a £100m "raid" on Welsh lottery funds in order to help pay for the 2012 Olympics.
"What can the people of Wales realistically expect for £427m they are paying for London Olympics," he added.
The prime minister said expenditure on Wales had grown "markedly" since Labour came to power in 1997.
He said Llwyd should be "grateful" for Labour's commitment to Wales.
Shona McIsaac (Lab, Cleethorpes) asked about policies to help Britain out of the recession.
Brown said that "when markets fail and banks falter," recovery was only possible by investing additional money.
Tim Yeo (Con, South Suffolk) asked whether the prime minister had instructed the chancellor to reverse the fall in green taxes he has presided over when Brown was at the Treasury.
"A tax is only a green tax if its primary purpose is to change behaviour rather than raise money," he told MPs.
Brown said the government had introduced a climate change levy, air passenger tax at a higher rate and had taken necessary measures to reduce carbon emissions.
"If he wants us to put VAT on fuel I would oppose him," he added.
Julie Morgan (Lab, Cardiff North) called for more civil service jobs to be relocated to her constituency.
Brown said the government wanted to help areas by creating jobs.
Calling on the prime minister to resign, Peter Tapsell (Con, Louth and Horncastle) said that the 300,000 troops now earmarked for operations in Afghanistan was exactly the number he had recommended would be necessary when the government first "recklessly" began operations.
Repeating an earlier joke at Nick Clegg's expense, Brown said US President Barack Obama would be grateful for his endorsement of the strategy.
But Tapsell has not always been right, he added.
"He advised me not to make the Bank of England independent," the prime minister reminded the House.
Dods Parliamentary Communications Ltd